A common flame retardant may worsen inflammation, which is important for people with MS.
Researchers studied a chemical called hexabromocyclododecane (HBCD), which is used to stop fires in things like furniture and electronics. They found that when human immune cells were exposed to HBCD, these cells produced more of two inflammatory substances called interleukin 1-beta and interleukin 6. Think of these substances as alarm signals that can cause the body to react more strongly, similar to how a smoke alarm alerts you to danger. This increased production of alarm signals was noticeable just 6 hours after exposure and continued to rise after 24 hours. The researchers discovered that the way HBCD makes these cells produce more signals involves changes in the cells' genetic instructions and certain pathways in the cells.
People with MS and their caregivers should pay attention to these findings because increased inflammation can worsen MS symptoms and lead to more flare-ups. Just like a small fire can grow bigger if not managed, increased inflammation can lead to more serious health issues. Caregivers can help by being aware of environmental exposure to chemicals like HBCD and advocating for safer living spaces. Healthcare providers might consider these findings when looking for ways to help manage inflammation in MS patients. Overall, avoiding exposure to harmful substances can be an important part of living well with MS.
The study only looked at human immune cells in a lab, not in real-life situations, so we don’t know how this affects people with MS directly. It’s also unclear how much HBCD exposure is needed to cause these effects, which means we should be cautious about making broad conclusions. Understanding these limitations is important because it reminds us that more research is needed to see the real impact on MS patients.
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Read MoreWhether you’ve recently been diagnosed with Multiple Sclerosis (MS) or are seeking to broaden your understanding of this complex, neurodegenerative disease, navigating the latest research can feel overwhelming. Studies published in respected medical journals like Journal of applied toxicology : JAT often range from early-stage, exploratory work to advanced clinical trials. These evidence-based findings help shape new disease-modifying therapies, guide symptom management techniques, and deepen our knowledge of MS progression.
However, not all research is created equal. Some clinical research studies may have smaller sample sizes, evolving methodologies, or limitations that warrant careful interpretation. For a more comprehensive, accurate understanding, we recommend reviewing the original source material—accessible via the More Details section above—and consulting with healthcare professionals who specialize in MS care.
By presenting a wide range of MS-focused studies—spanning cutting-edge treatments, emerging therapies, and established best practices—we aim to empower patients, caregivers, and clinicians to stay informed and make well-informed decisions when managing Multiple Sclerosis.