Getting treated for MS with disease-modifying therapies can help slow down progression to more severe stages.
Over 30 years, researchers studied nearly 10,000 MS patients to see how the disease changes over time. They found that many patients who did not receive disease-modifying therapies (DMTs) were more likely to experience a worsening of their condition. For example, about 10% of untreated patients reached a more severe stage of MS, compared to only about 5% of those who were treated. Additionally, the number of patients moving to this more severe stage has decreased over the years, thanks to better treatment options. This shows that staying on treatment can really make a difference in managing MS.
MS patients and caregivers should pay attention to these findings because they highlight the importance of using treatments. Just like regular check-ups help keep your car running smoothly, staying on MS treatments can help keep your health stable. Caregivers can support patients by ensuring they understand the importance of these therapies in preventing disease progression. Healthcare providers can use this information to encourage patients to stick with their treatments and monitor their progress. In everyday life, this means better management of symptoms and potentially a more active lifestyle.
While this study provides important insights, it mainly focused on patients in Italy, which might not reflect experiences in other countries. The study also shows trends over a long time, but each person's MS journey is unique, so results may vary for individuals. Finally, more research is needed to find out how to better support patients as their disease progresses.
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Read MoreWhether you’ve recently been diagnosed with Multiple Sclerosis (MS) or are seeking to broaden your understanding of this complex, neurodegenerative disease, navigating the latest research can feel overwhelming. Studies published in respected medical journals like Journal of neurology, neurosurgery, and psychiatry often range from early-stage, exploratory work to advanced clinical trials. These evidence-based findings help shape new disease-modifying therapies, guide symptom management techniques, and deepen our knowledge of MS progression.
However, not all research is created equal. Some clinical research studies may have smaller sample sizes, evolving methodologies, or limitations that warrant careful interpretation. For a more comprehensive, accurate understanding, we recommend reviewing the original source material—accessible via the More Details section above—and consulting with healthcare professionals who specialize in MS care.
By presenting a wide range of MS-focused studies—spanning cutting-edge treatments, emerging therapies, and established best practices—we aim to empower patients, caregivers, and clinicians to stay informed and make well-informed decisions when managing Multiple Sclerosis.