30 Active TrialsLarge Center
3 MS centers statewide · Ranked #1 in Missouri for clinical trials · #2 in Missouri for provider count
What kind of place is this?
Part of Major Health SystemComprehensive Care TeamResearch Focused
You're in a large academic MS center where your care is shaped by a broad neurology team and close ties to major hospitals. You'll likely appreciate having access to adult and pediatric neurology, plus related specialties like neuroimmunology and neuro infectious disease.
Facility Profile
Synthesized from this facility's public website and data sources. Not a recommendation or ranking — just a summary to help you orient.
Direct Doctor Access2/5
Support Services2/5
Clinical Trials & Research3/5
Insurance & Navigation Help1/5
Scheduling & Virtual Care2/5
About John L. Trotter Multiple Sclerosis Center
This center stands out for being embedded in a major academic health system with both adult and pediatric neurology support. It also connects MS care with related specialties like neuroimmunology and neuro infectious disease.
John L. Trotter Multiple Sclerosis Center provides multiple sclerosis care in Saint Louis through a large academic neurology team. Patients can access adult and pediatric neurology, neuroimmunology, and neuro infectious disease expertise in one connected system. The center is part of Washington University in St. Louis, WashU Medicine, and Barnes-Jewish Hospital, with St. Louis Children’s Hospital also part of its care network. It is a good fit for people who want MS care from a major academic medical center with broad neurology support.
Good to know
- Call 314-362-3293 to schedule MS care.
- Part of Washington University in St. Louis and WashU Medicine.
- Connected with Barnes-Jewish Hospital and St. Louis Children’s Hospital.
- Adult and pediatric neurology are both part of the care team.
John L. Trotter Multiple Sclerosis Center in Saint Louis is part of Washington University in St. Louis and WashU Medicine, with care connected to Barnes-Jewish Hospital and St. Louis Children's Hospital. You can expect MS care within a large academic neurology department that also includes adult neurology, pediatric neurology, neuroimmunology, and neuro infectious disease. This makes the center especially well suited for people who may need input from more than one neurology specialty.
Featured Care Team Members
Matthew Brier, MD
Active MS Prescriber
Anne Cross, MD
Active MS Prescriber
Robert Naismith, MD
Active MS Prescriber
Gregory Wu, MD
Active MS Prescriber
Services & Treatments
What They Treat
multiple sclerosis
How They Treat It
Multiple sclerosis careAdult neurologyPediatric neurologyNeuroimmunologyNeuro infectious diseaseNeurology consultations
Diagnostics
electroencephalography (EEG)electromyography (EMG)positron emission tomography (PET)
Research & Clinical Trials
This center is currently involved in 30 clinical trials — ranked #1 in Missouri for active trials
A Rollover Study to Evaluate the Long-Term Safety and Efficacy of Ocrelizumab In Patients With Multiple Sclerosis
Hoffmann-La Roche
ACTIVE NOT RECRUITINGPHASE3
Ocrelizumab
A Study of Ocrelizumab in Children and Adolescents With Relapsing-Remitting Multiple Sclerosis
Hoffmann-La Roche
ACTIVE NOT RECRUITINGPHASE2
Ocrelizumab
A Study to Evaluate Ocrelizumab Treatment in Participants With Progressive Multiple Sclerosis
Hoffmann-La Roche
ACTIVE NOT RECRUITINGPHASE3
Ocrelizumab
A Study to Evaluate Safety and Efficacy of Ocrelizumab in Comparison With Fingolimod in Children and Adolescents With Relapsing-Remitting Multiple Sclerosis (RRMS)
Hoffmann-La Roche
ACTIVE NOT RECRUITINGPHASE3
OcrelizumabOcrelizumab PlaceboFingolimodFingolimod Placebo
A Study to Evaluate the Efficacy and Safety of Fenebrutinib Compared With Ocrelizumab in Adult Participants With Primary Progressive Multiple Sclerosis
Hoffmann-La Roche
ACTIVE NOT RECRUITINGPHASE3
FenebrutinibOcrelizumabPlacebo matched to ocrelizumabPlacebo matched to fenebrutinib
A Study to Evaluate the Efficacy and Safety of Fenebrutinib Compared With Teriflunomide in Relapsing Multiple Sclerosis (RMS)
Hoffmann-La Roche
ACTIVE NOT RECRUITINGPHASE3
FenebrutinibTeriflunomidePlacebo
A Study to Evaluate the Efficacy, Safety and Pharmacokinetics (PK) of a Higher Dose of Ocrelizumab in Adults With Primary Progressive Multiple Sclerosis (PPMS)
Hoffmann-La Roche
ACTIVE NOT RECRUITINGPHASE3
OcrelizumabOcrelizumabAntihistamineMethylprednisolone
A Study to Evaluate the Efficacy, Safety and Pharmacokinetics (PK) of a Higher Dose of Ocrelizumab in Adults With Relapsing Multiple Sclerosis (RMS)
Hoffmann-La Roche
ACTIVE NOT RECRUITINGPHASE3
OcrelizumabOcrelizumabAntihistamineMethylprednisolone
A Study to Evaluate the Efficacy, Safety and Tolerability of BMS-986368 in Participants With Multiple Sclerosis Spasticity
Celgene
RECRUITINGPHASE2
BMS-986368Placebo
A Study to Evaluate the Safety, Tolerability, Cellular Kinetics, and Pharmacodynamics of P-CD19CD20-ALLO1 in Participants With Multiple Sclerosis
Genentech, Inc.
RECRUITINGPHASE1
P-CD19CD20-ALLO1 CellsCyclophosphamideFludarabine
A Study to Evaluate the Safety, Tolerability, Efficacy, and Drug Levels of CC-97540 in Participants With Relapsing Forms of Multiple Sclerosis, Progressive Forms of Multiple Sclerosis or Refractory Myasthenia Gravis (MG) (Breakfree-2)
Juno Therapeutics, Inc., a Bristol-Myers Squibb Company
RECRUITINGPHASE1
CC-97540FludarabineCyclophosphamide
A Study to Investigate Multiple Sclerosis Relapse Prevention With mRNA-1195 Compared With Placebo in Participants Aged 18 to ≤55 Years
ModernaTX, Inc.
RECRUITINGPHASE2
mRNA-1195Placebo
Best Available Therapy Versus Autologous Hematopoietic Stem Cell Transplant for Multiple Sclerosis (BEAT-MS)
National Institute of Allergy and Infectious Diseases (NIAID)
RECRUITINGPHASE3
Autologous Hematopoietic Stem Cell TransplantationBest Available Therapy (BAT)
Central Vein Sign: a Diagnostic Biomarker in Multiple Sclerosis
The Cleveland Clinic
ACTIVE NOT RECRUITING
MRI
Efficacy and Safety Studies of Frexalimab (SAR441344) in Adults With Relapsing Forms of Multiple Sclerosis
Sanofi
RECRUITINGPHASE3
FrexalimabTeriflunomidePlacebo infusionPlacebo tabletMRI contrast-enhancing agentsCholestyramineActivated charcoal
Efficacy and Safety Study of Frexalimab (SAR441344) in Adults With Nonrelapsing Secondary Progressive Multiple Sclerosis
Sanofi
RECRUITINGPHASE3
FrexalimabPlaceboMRI contrast-enhancing agents
Efficacy and Safety of Remibrutinib After Switching From Ocrelizumab in Participants Living With Relapsing Multiple Sclerosis.
Novartis Pharmaceuticals
RECRUITINGPHASE3
Remibrutinib oral treatmentOcrelizumab
Functional Outcomes From Diets in Multiple Sclerosis
University of Alabama at Birmingham
ACTIVE NOT RECRUITINGNA
Glycemic loadCalorie restrictionBehavioral support
Long-term Safety, Tolerability and Effectiveness Study of Ofatumumab in Patients With Relapsing MS
Novartis Pharmaceuticals
ACTIVE NOT RECRUITINGPHASE3
OfatumumabTetanus toxoid (TT) containing vaccine (Td, Tdap)13-valent pneumococcal conjugate vaccine (13-PCV)23-valent pneumococcal polysaccharide vaccine (23-PPV)Seasonal Quadrivalent influenza vaccineKeyhole limpet hemocyanin (KLH) neo-antigen
MS-DETECT: Early Detection of Multiple Sclerosis Progression With MSCopilot® Detect
Ad scientiam
ACTIVE NOT RECRUITINGNA
MSCopilot® Detect mobile application
MSCopilot Users' Feedback in Real Life - Outcomes Regarding Integration in Patients' pathWay and Users' ExpeRience
Ad scientiam
ACTIVE NOT RECRUITINGNA
MSCopilot Flower mobile application
Nivolumab in Treating Patients With Autoimmune Disorders and Advanced, Metastatic, or Unresectable Cancer
National Cancer Institute (NCI)
RECRUITINGPHASE1
Biospecimen CollectionNivolumab
Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of a New Maintenance Dosing Regimen of Ofatumumab
Novartis Pharmaceuticals
ACTIVE NOT RECRUITINGPHASE3
Ofatumumab approved doseOfatumumab new dose
Phase 2 Basket Trial of Nab-sirolimus in Patients With Malignant Solid Tumors With Pathogenic Alterations in TSC1/TSC2 Genes (PRECISION 1)
Aadi Bioscience, Inc.
ACTIVE NOT RECRUITINGPHASE2
nab-sirolimus
Smoldering Inflammation in MS
Washington University School of Medicine
RECRUITING
Radiotracer [11C]-CS1P1Radiotracer [11C]-DPA-713anti-CD20 MS treatmentRadiotracer [12F]-FDG
Stopping TSC Onset and Progression 2B: Sirolimus TSC Epilepsy Prevention Study
Darcy Krueger
RECRUITINGPHASE2
SirolimusPlacebo
Study of COYA 302 for the Treatment of ALS
Coya Therapeutics
RECRUITINGPHASE2
COYA 302Placebo
TSC Biosample Repository and Natural History Database
National Tuberous Sclerosis Association
RECRUITING
PhlebotomyBuccal (cheek) swabGenetic TestingTissue donation after routine clinical procedure
This Study Involves a Positron Emission Tomography (PET) Scan Using a New Investigational Radioactive Tracer, [18F]-FZTA, to Detect Inflammation in the Brain. The Tracer Will be Tested in Healthy Younger Adults and Individuals With Multiple Sclerosis.
Washington University School of Medicine
RECRUITING
[18F] FZTA
Treatment of Participants With Primary or Secondary Progressive Multiple Sclerosis
Tr1X, Inc.
RECRUITINGPHASE1, PHASE2
TRX319Bendamustine
Insurance & Access
Insurance & Support
Related MS Research
Recent studies relevant to this center's focus areas
FAQs from John L. Trotter Multiple Sclerosis Center
You can call 314-362-3293 to arrange MS care. This is the main appointment line provided for the center.
Yes. The neurology department includes both adult neurology and pediatric neurology, and St. Louis Children’s Hospital is part of the care network.
In addition to multiple sclerosis care, the center offers adult neurology, pediatric neurology, neuroimmunology, neuro infectious disease, and neurology consultations.
Compare Missouri MS Centers
| Center | Type | Infusion | Virtual | Experience |
|---|---|---|---|---|
John L. Trotter Multiple Sclerosis Center Saint Louis | Academic MS Center | — | — | 2/5 |
| Dedicated MS Practice | — | — | 3.4/5 | |
| Community Hospital Program | — | — | 2.2/5 |
John L. Trotter Multiple Sclerosis Center
Saint Louis • Academic MS Center
Infusion
—
Virtual
—
Experience
2/5
Saint Luke's Marion Bloch Neuroscience Institute
Kansas City • Dedicated MS Practice
Infusion
—
Virtual
—
Experience
3.4/5
Mercy Hospital St. Louis / Mercy Clinic Neurology
Chesterfield • Community Hospital Program
Infusion
—
Virtual
—
Experience
2.2/5
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Information on this page is compiled from public sources including facility websites, ClinicalTrials.gov, CMS data, and AI analysis. It may not be complete or current. Always verify directly with the facility.