19 Active TrialsLarge Center
15 MS centers statewide · Ranked #1 in Massachusetts for clinical trials · #2 in Massachusetts for provider count
What kind of place is this?
Comprehensive Care TeamResearch FocusedPart of Major Health System
You’re looking at a large academic MS center where your care is shaped by a team of specialists working together. You’ll likely appreciate the depth of expertise, the range of diagnostic testing, and access to rehabilitation, neuroimmunology, and research support. You may want to plan for a busier academic setting and a few extra steps during intake and follow-up.
Facility Profile
Synthesized from this facility's public website and data sources. Not a recommendation or ranking — just a summary to help you orient.
Direct Doctor Access2/5
Support Services5/5
Clinical Trials & Research5/5
Insurance & Navigation Help3/5
Scheduling & Virtual Care3/5
About Massachusetts General Hospital MS Clinic
This is a major academic MS center tied to Massachusetts General Hospital, with a broad multidisciplinary team and multiple fellowship and research programs. It also cares for related conditions such as neuromyelitis optica spectrum disorder and MOGAD.
This clinic provides diagnosis, treatment, and follow-up care for multiple sclerosis and related neuroimmunology conditions. Patients are seen by a large academic team that can support medical treatment, symptom management, rehabilitation, and specialty input when needed. Diagnostic care can include blood tests, MRI of the brain and spinal cord, lumbar puncture, and neurologic exams. The clinic also has fellowship programs, an imaging lab, and a research and clinical trials program, reflecting its strong academic focus.
Good to know
- You can be seen without a referral, with additional intake steps for new patients.
- Bring prior brain and spinal cord MRI images to your first visit.
- Existing patients can use Patient Gateway to view appointments, message the care team, and pay bills.
- The clinic works with primary care physicians and neurologists for ongoing care.
Massachusetts General Hospital MS Clinic in Boston is an academic multiple sclerosis center that cares for people with MS, neuromyelitis optica spectrum disorder, MOGAD, and other autoimmune conditions. You can expect care from a multidisciplinary team that includes neurology, nursing, physical therapy, occupational therapy, psychology, neuroradiology, urology, neuro-ophthalmology, and social work.
Featured Care Team Members
Rebecca Gillani, MD, PhD
Instructor of Neurology
Neurology
Eric Klawiter, MD
Director, Multiple Sclerosis and Neuromyelitis Optica Unit
Multiple sclerosis
Michael Levy, MD, PhD
Research Director, Division of Neuroimmunology & Neuroinfectious Disease; Director, Neuroimmunology Clinic and Research Laboratory
Neuroimmunology
Marcelo Matiello, MD
Associate Professor of Neurology; Vice-Chair of Clinical Affairs; Senior Clinical Neurologist
Neurology
Tanuja Chitnis, MD
Active MS Prescriber
Rebecca Gillani, MD
Active MS Prescriber
Eric Klawiter, MD
Active MS Prescriber
Michael Levy, MD, PhD
Active MS Prescriber
Specialized Programs
Multiple Sclerosis Fellowship Program
MS and Neuroimmunology Fellowship Program
Research and clinical trials program
Multiple Sclerosis Imaging Lab
Neuroimmunology Clinic and Research Laboratory
Partnerships & Referral Network
- Mass General Brigham MS and Neuroimmunology Fellowship Program
Services & Treatments
What They Treat
Multiple sclerosisNeuromyelitis optica spectrum disorderMOGAD
How They Treat It
Comprehensive diagnosisMultiple sclerosis treatmentMS care overviewReferral information for providersInitial appointment evaluationFollow-up careDisease-modifying therapiesOral medicationsInfusionsInjectionsPhysical therapyOccupational therapyMedications for symptom management
Diagnostics
Blood testsMRI of the brainMRI of the spinal cordLumbar punctureClinical evaluationNeurologic examPhysical exam
Research & Clinical Trials
This center is currently involved in 19 clinical trials — ranked #1 in Massachusetts for active trials
A Rollover Study to Evaluate the Long-Term Safety and Efficacy of Ocrelizumab In Patients With Multiple Sclerosis
Hoffmann-La Roche
ACTIVE NOT RECRUITINGPHASE3
Ocrelizumab
A Study to Evaluate Ocrelizumab Treatment in Participants With Progressive Multiple Sclerosis
Hoffmann-La Roche
ACTIVE NOT RECRUITINGPHASE3
Ocrelizumab
A Study to Evaluate the Efficacy, Safety and Pharmacokinetics (PK) of a Higher Dose of Ocrelizumab in Adults With Primary Progressive Multiple Sclerosis (PPMS)
Hoffmann-La Roche
ACTIVE NOT RECRUITINGPHASE3
OcrelizumabOcrelizumabAntihistamineMethylprednisolone
A Study to Evaluate the Safety and Pharmacokinetics of Single and Multiple Doses of Prosetin in Healthy Volunteers and Participants With ALS
ProJenX
RECRUITINGPHASE1
prosetinplacebo
A Study to Investigate Behavioral and Other Co-Occurring Outcomes With Epidiolex as Add-On Therapy in Participants Aged 1 to 65 Years of Age With Tuberous Sclerosis Complex
Jazz Pharmaceuticals
ACTIVE NOT RECRUITINGPHASE4
Cannabidiol Oral Solution [Epidiolex]
AMT-260 Gene Therapy Study in Adults With Unilateral Refractory Mesial Temporal Lobe Epilepsy
UniQure Biopharma B.V.
RECRUITINGPHASE1, PHASE2
AAV9-hSyn1-miGRIK2
AMX0114 in Adult Participants With Amyotrophic Lateral Sclerosis
Amylyx Pharmaceuticals Inc.
RECRUITINGPHASE1
AMX0114Placebo
Care in Multiple Sclerosis (MS)
NYU Langone Health
RECRUITING
Effects of Antiviral Therapies on Epstein-Barr Virus Replication
Massachusetts General Hospital
ENROLLING BY INVITATIONPHASE2
Truvada (tenofovir/emtricitabine)
Efgartigimod for the Treatment of Acute Optic Neuritis
Anastasia Vishnevetsky, MD, MPH
RECRUITINGPHASE2
Efgartigimod AlfaPlacebo
Genes and Environment in Multiple Sclerosis
Columbia University
RECRUITING
Investigating the Utility of Demyelination Tracer [18F]3F4AP in Controls and Multiple Sclerosis Subjects
Massachusetts General Hospital
RECRUITINGPHASE1
F-18 3F4AP
Nivolumab in Treating Patients With Autoimmune Disorders and Advanced, Metastatic, or Unresectable Cancer
National Cancer Institute (NCI)
RECRUITINGPHASE1
Biospecimen CollectionNivolumab
Ocrelizumab Discontinuation in Relapsing Multiple Sclerosis
National Institute of Allergy and Infectious Diseases (NIAID)
RECRUITINGPHASE4
OcrelizumabPlacebo for Ocrelizumab
Safety and Efficacy of Fingolimod in Pediatric Patients With Multiple Sclerosis
Novartis Pharmaceuticals
ACTIVE NOT RECRUITINGPHASE3
Interferon beta-1aFingolimodPlacebo capsulePlacebo i.m. injection
Study of COYA 302 for the Treatment of ALS
Coya Therapeutics
RECRUITINGPHASE2
COYA 302Placebo
TSC Biosample Repository and Natural History Database
National Tuberous Sclerosis Association
RECRUITING
PhlebotomyBuccal (cheek) swabGenetic TestingTissue donation after routine clinical procedure
Tibulizumab Systemic Sclerosis Understanding and Response Evaluation (TibuSURE)
Zura Bio Inc
RECRUITINGPHASE2
TibulizumabPlacebo
Traditional Versus Early Aggressive Therapy for Multiple Sclerosis Trial
Johns Hopkins University
ACTIVE NOT RECRUITINGNA
Natalizumab/natalizumab-sztn, Alemtuzumab, Ocrelizumab, Rituximab/rituximab-arrx/rituximab-abbs/rituximab-pvvr, Cladribine, Ofatumumab, Ublituximab-xiiy, Ocrelizumab and hyaluronidase-ocsqGlatiramer acetate, Interferons (intramuscular, subcutaneous, pegylated) Teriflunomide, Fumarates (dimethyl, diroximel, monomethyl) Fingolimod, Siponimod, Ozanimod, Ponesimod
Insurance & Access
Insurance & Support
Patient Portal
Related MS Research
Recent studies relevant to this center's focus areas
FAQs from Massachusetts General Hospital MS Clinic
The clinic treats multiple sclerosis, neuromyelitis optica spectrum disorder, MOGAD, and other autoimmune conditions. Care is designed for people who need both diagnosis and ongoing treatment support.
No referral is required to access care. New patients can be seen after additional intake steps, and the clinic also works with primary care physicians and neurologists for ongoing care.
Evaluation can include blood tests, MRI of the brain, MRI of the spinal cord, lumbar puncture, and a full neurologic and physical exam. These tests help the team confirm a diagnosis and guide treatment.
Treatment options include disease-modifying therapies, oral medications, infusions, injections, and medications for symptom management. The clinic also offers physical therapy and occupational therapy as part of care.
Existing patients can use Patient Gateway to view appointments, message the care team, and pay bills. This can make follow-up care easier to manage between visits.
Compare Massachusetts MS Centers
| Center | Type | Infusion | Virtual | Experience |
|---|---|---|---|---|
Massachusetts General Hospital MS Clinic Boston | Academic MS Center | — | — | 3.6/5 |
| Academic MS Center | — | — | 3.6/5 | |
| Dedicated MS Practice | — | — | 3.4/5 | |
| Academic MS Center | — | — | 3.4/5 | |
Lahey Multiple Sclerosis Center Burlington | Dedicated MS Practice | — | — | 3/5 |
| Dedicated MS Practice | — | — | 2/5 |
Massachusetts General Hospital MS Clinic
Boston • Academic MS Center
Infusion
—
Virtual
—
Experience
3.6/5
Boston Medical Center MS Center
Boston • Academic MS Center
Infusion
—
Virtual
—
Experience
3.6/5
UMass Memorial Medical Center MS Clinic
Worcester • Dedicated MS Practice
Infusion
—
Virtual
—
Experience
3.4/5
Brigham Multiple Sclerosis Center
Boston • Academic MS Center
Infusion
—
Virtual
—
Experience
3.4/5
Lahey Multiple Sclerosis Center
Burlington • Dedicated MS Practice
Infusion
—
Virtual
—
Experience
3/5
Tufts Medicine MS Program
Boston • Dedicated MS Practice
Infusion
—
Virtual
—
Experience
2/5
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Information on this page is compiled from public sources including facility websites, ClinicalTrials.gov, CMS data, and AI analysis. It may not be complete or current. Always verify directly with the facility.