Tests & Procedures

Lumbar Puncture

What it is

A lumbar puncture, sometimes called a spinal tap, is a test where a small amount of fluid is taken from around the spinal cord using a thin needle in the lower back. The fluid is checked for signs of inflammation and immune activity. Numbing medicine is used, and the test usually takes less than an hour.

What you might notice

People are usually positioned curled on their side or sitting while leaning forward. After numbing medicine, there is brief pressure in the lower back. Some clinics include a period of lying flat afterward to reduce the chance of a headache.

Why it matters for you

Not everyone needs a lumbar puncture for an MS diagnosis, but some do. Knowing what it looks for helps you understand why it might be part of your workup.

Questions to ask your doctor

  • What type of MS do I have, and how confident are you in the diagnosis?
  • Would a second opinion be reasonable? Can you recommend one?
  • What is my likely prognosis over the next 5 to 10 years?
  • Is MS going to shorten my life?
  • What is my risk of eventually needing a wheelchair or mobility aid?
See all you just got diagnosed questions

Find MS treatment centers near you

MS care is specialized — the center you choose shapes access to DMTs, infusions, and clinical trials. Pick your state to see centers in your area.

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Reviewed by the MS Buddy editorial team · Last updated April 16, 2026
Not medical advice. Always consult your care team.