UCSF Multiple Sclerosis Center

San Francisco, California

Academic MS Center
23 Active TrialsVirtual CareLarge Center
30 MS centers statewide · Ranked #1 in California for clinical trials · #3 in California for provider count
What kind of place is this?
Comprehensive Care TeamResearch FocusedVirtual Care Available

You’ll find an academic MS center where care is built around neurology expertise, testing, and team-based support. You’ll likely appreciate the range of services, including second opinions, virtual visits, rehab therapies, and access to specialists across related conditions.

Facility Profile
Synthesized from this facility's public website and data sources. Not a recommendation or ranking — just a summary to help you orient.
Direct Doctor Access2/5
Support Services5/5
Clinical Trials & Research5/5
Insurance & Navigation Help3/5
Scheduling & Virtual Care4/5

About UCSF Multiple Sclerosis Center

This center combines UCSF’s academic neurology expertise with a broad neuroinflammation program and care for both adults and children. It also serves an international patient population and offers virtual visits, second opinions, and a strong support-services network.

UCSF Multiple Sclerosis Center treats multiple sclerosis and a wide range of related neuroinflammatory conditions, including neuromyelitis optica, optic neuritis, transverse myelitis, autoimmune encephalitis, and other demyelinating disorders. You can access advanced testing such as MRI, lumbar puncture, evoked potentials, and neurocognitive evaluation, along with personalized treatment planning and symptom management. The center also offers physical therapy, occupational therapy, rehabilitative medicine, and support services to help you manage daily life with MS. It stands out for its academic setting, multidisciplinary team, and care for patients from over 30 countries.

UCSF Multiple Sclerosis Center in San Francisco is an academic MS and neuroinflammation center affiliated with UCSF Health and UCSF School of Medicine. You can expect a team approach that includes neurology, neuropsychology, rehabilitation, social work, and other specialty support. Patients come from around the world for its MS expertise and access to advanced diagnostics, second opinions, and virtual care.

Featured Care Team Members

Riley M. Bove, MD, MS
Neurologist
Neuroimmunology / Neurology
Bruce Cree, MD, PhD
Clinical research director
Neuroimmunology / Neurology
Jeffrey M. Gelfand, MD
Medical director
Neuroimmunology / Neurology
Douglas S. Goodin, MD
Neurologist
Neuroimmunology / Neurology / Clinical Neurophysiology
Riley Bove, MD
Active MS Prescriber

Specialized Programs

Pediatric MS care
Support services
Patient and family advisory council
Neuroinflammation care
Clinical research participation

Services & Treatments

What They Treat
Multiple sclerosisNeuromyelitis opticaOptic neuritisTransverse myelitisAutoimmune encephalitisMeningitisEncephalitisDemyelinating diseaseNeuroinflammatory disordersLeukodystrophy
How They Treat It
Multiple sclerosis careNeuroinflammation careSecond opinionsAdvanced diagnosticsPersonalized treatment planningSymptom managementPhysical therapyOccupational therapyRehabilitative medicineNeuropsychologySupport servicesClinical trial participationBeta interferonGlatiramer acetateImmunosuppressive drugsBotox for spasticityMultiple sclerosis rehabilitationExercise therapyOccupational therapyPhysical therapyStress reduction
Diagnostics
MRIBlood testsUrine testsLumbar punctureEvoked potentialsNeurocognitive evaluationMovement testsVision testsWalking and functional testsNeurodiagnostic testing

Research & Clinical Trials

This center is currently involved in 23 clinical trials — ranked #1 in California for active trials

"Selfie" Videos: A Novel, Patient-centered, Comprehensive Approach to Measuring Function in MS
University of California, San Francisco
RECRUITING
A Closed Loop, Doctor to Patient, Mobile Application for Depression in People With Multiple Sclerosis
University of California, San Francisco
ACTIVE NOT RECRUITINGNA
MS CATCH
A Rollover Study to Evaluate the Long-Term Safety and Efficacy of Ocrelizumab In Patients With Multiple Sclerosis
Hoffmann-La Roche
ACTIVE NOT RECRUITINGPHASE3
Ocrelizumab
A Study of KYV-101, a CD19 CAR T Cell Therapy, in Participants With Treatment Refractory Progressive Multiple Sclerosis
Bruce Cree
ACTIVE NOT RECRUITINGPHASE1
KYV-101 (Biological) - 0.33 ×10^8 cellsKYV-101 (Biological) - 1 ×10^8 cellsChemotherapy: cyclophosphamide (CYC)Chemotherapy: fludarabine (FLU)
A Study to Evaluate Ocrelizumab Treatment in Participants With Progressive Multiple Sclerosis
Hoffmann-La Roche
ACTIVE NOT RECRUITINGPHASE3
Ocrelizumab
A Study to Evaluate Safety and Efficacy of Ocrelizumab in Comparison With Fingolimod in Children and Adolescents With Relapsing-Remitting Multiple Sclerosis (RRMS)
Hoffmann-La Roche
ACTIVE NOT RECRUITINGPHASE3
OcrelizumabOcrelizumab PlaceboFingolimodFingolimod Placebo
Assessing Changes in Multi-parametric MRI in MS Patients Taking Clemastine Fumarate as a Myelin Repair Therapy
University of California, San Francisco
RECRUITINGPHASE1, PHASE2
Clemastine FumaratePlacebo
Assessment of Clemastine Fumarate as a Remyelinating Agent in Acute Optic Neuritis (ReCOVER)
University of California, San Francisco
RECRUITINGPHASE2
ClemastinePlacebo
Care in Multiple Sclerosis (MS)
NYU Langone Health
RECRUITING
Concentration of Ofatumumab in the Breast Milk of Lactating Women With Relapsing Forms of Multiple Sclerosis
Novartis Pharmaceuticals
ACTIVE NOT RECRUITINGPHASE4
Ofatunumab
ECoG BMI for Motor and Speech Control
Karunesh Ganguly
RECRUITINGNA
PMT/Blackrock Combination Device
Effects of Ocrelizumab Treatment on Immune Cells in Lymph Nodes in Multiple Sclerosis
University of California, San Francisco
ENROLLING BY INVITATIONPHASE4
Ocrelizumab
Impact of Ocrelizumab on Cerebrospinal Fluid Biomarkers at Multiple Sclerosis Onset
University of California, San Francisco
ACTIVE NOT RECRUITINGPHASE4
Ocrelizumab
Multiple Sclerosis Falls Insight Track
University of California, San Francisco
ACTIVE NOT RECRUITINGNA
MS FIT: Falls Insight Track
Neuroprotection With N-acetyl Cysteine for Patients With Progressive Multiple Sclerosis
Emmanuelle Waubant, MD PhD
ACTIVE NOT RECRUITINGPHASE2
N-acetyl cysteinePlacebo
Phase 2 Study Evaluating Rapcabtagene Autoleucel in Participants With Diffuse Cutaneous Systemic Sclerosis
Novartis Pharmaceuticals
RECRUITINGPHASE2
rapcabtagene autoleucelrituximab
Pregnancy Registry, Infants, Serum/Milk Analysis (PRISMA)
University of California, San Francisco
RECRUITING
Roll-over Study to Collect and Assess Long-term Safety of Everolimus in Patients With TSC and Refractory Seizures Who Have Completed the EXIST-3 Study [CRAD001M2304] and Who Are Benefitting From Continued Treatment
Novartis Pharmaceuticals
ACTIVE NOT RECRUITINGPHASE3
everolimus
Safety and Efficacy of Fingolimod in Pediatric Patients With Multiple Sclerosis
Novartis Pharmaceuticals
ACTIVE NOT RECRUITINGPHASE3
Interferon beta-1aFingolimodPlacebo capsulePlacebo i.m. injection
Safety, PK and Biodistribution of 18F-OP-801 in Patients With ALS, AD, MS, PD and Healthy Volunteers
Ashvattha Therapeutics, Inc.
RECRUITINGPHASE1, PHASE2
18F-OP-801
Traditional Versus Early Aggressive Therapy for Multiple Sclerosis Trial
Johns Hopkins University
ACTIVE NOT RECRUITINGNA
Natalizumab/natalizumab-sztn, Alemtuzumab, Ocrelizumab, Rituximab/rituximab-arrx/rituximab-abbs/rituximab-pvvr, Cladribine, Ofatumumab, Ublituximab-xiiy, Ocrelizumab and hyaluronidase-ocsqGlatiramer acetate, Interferons (intramuscular, subcutaneous, pegylated) Teriflunomide, Fumarates (dimethyl, diroximel, monomethyl) Fingolimod, Siponimod, Ozanimod, Ponesimod
VIRtual Versus UsuAL In-office Care for Multiple Sclerosis (VIRTUAL-MS)
The Cleveland Clinic
ACTIVE NOT RECRUITINGNA
Multiple Sclerosis Clinical Care Delivery via telehealthMultiple Sclerosis Clinical Care Delivery via standard in clinic visits
Wearables for the Bladder: an In-home Treatment Feasibility Pilot Study
University of California, San Francisco
ACTIVE NOT RECRUITINGNA
WeBStandard pelvic floor physical therapy

Insurance & Access

Contact
1651 4th Street Suite 252, San Francisco, CA 94158
Insurance & Support
Care Coordinator
Support Groups

FAQs from UCSF Multiple Sclerosis Center

Yes. The center treats neuromyelitis optica, optic neuritis, transverse myelitis, autoimmune encephalitis, meningitis, encephalitis, demyelinating disease, neuroinflammatory disorders, and leukodystrophy.

You can access MRI, blood tests, urine tests, lumbar puncture, evoked potentials, neurocognitive evaluation, movement tests, vision tests, walking and functional tests, and other neurodiagnostic testing.

Yes. Second opinions are available, and patients can schedule online for care with the center.

Support includes physical therapy, occupational therapy, rehabilitative medicine, neuropsychology, psychology support, social work support, nutrition recommendations, stress management, and an MS support group.

Named physicians include Riley M. Bove, MD, MS; Bruce Cree, MD, PhD; Jeffrey M. Gelfand, MD; and Douglas S. Goodin, MD. The center also has multidisciplinary support across several specialties.

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