6 Active TrialsVirtual CareLarge Center
30 MS centers statewide · Ranked #8 in California for clinical trials · #1 in California for provider count
What kind of place is this?
Comprehensive Care TeamResearch FocusedVirtual Care Available
You’re looking at an academic MS center with a multidisciplinary team built around complex neuroimmune care. You may appreciate the range of specialists, telehealth visits, and access to a fellowship-trained environment. Because this is an academic center, appointments can be more specialized and less like a small neighborhood clinic.
Facility Profile
Synthesized from this facility's public website and data sources. Not a recommendation or ranking — just a summary to help you orient.
Direct Doctor Access2/5
Support Services5/5
Clinical Trials & Research5/5
Insurance & Navigation Help4/5
Scheduling & Virtual Care4/5
About USC Multiple Sclerosis Comprehensive Care Center
This center stands out for combining a large multidisciplinary team with academic ties to USC, Keck Medicine, and the Keck School of Medicine. It also has a dedicated NMO and MOG clinic led by a subspecialty director, plus a fellowship program that supports advanced MS care.
This USC center cares for people with multiple sclerosis, neuromyelitis optica spectrum disorder, MOG antibody-associated disease, autoimmune encephalitis, and other complex neuroimmune conditions. Patients can access services such as occupational therapy, physical therapy, neuropsychology, neuroradiology, psychiatry, rheumatology, urology, and specialty pharmacy support. The team also offers telehealth visits, educational resources, and a multidisciplinary approach that brings several specialties together in one place. Its affiliations with USC and Keck Medicine reflect a strong academic and specialty-care setting.
Good to know
- Telehealth appointments are available.
- Offers a multiple sclerosis fellowship program.
- Works closely with USC, Keck Medicine of USC, and the Keck School of Medicine.
USC MS and Neuroimmunology Center is an academic MS program in Los Angeles connected to Keck Medicine of USC and the Keck School of Medicine. You'll find care for multiple sclerosis and related autoimmune neurologic conditions, with support from a broad team that includes neurology, neuro-ophthalmology, rehabilitation, social work, and more. Telehealth appointments and a fellowship program add to its specialty-focused care.
Featured Care Team Members
Lilyana Amezcua, MD
Chief of the Multiple Sclerosis and Neuroimmunology Division; medical director of the Neuromyelitis Optica and MOG clinic
Neurology/Neuroimmunology
Masoud Majed, MD
Neurology/Neuroimmunology
Jeffrey Alan Gluckstein, MD
Neuro-ophthalmology
Christina J. Azevedo, MD
Fellowship Director
Multiple sclerosis and other autoimmune disorders of the central nervous system
Christopher Orlando, MD, MPH
Multiple sclerosis and related autoimmune disorders of the central nervous system
Leslie Jane Tarlow, NP-C
Nurse Practitioner and MS provider
Multiple sclerosis
Rebecca Cunningham, OTD, OTR/L, MSCS
Occupational therapy
Nora Darakjian, PT, DPT
Physical therapy
Kara Lynn Barton, MSW, LCSW
Licensed social worker
Social work
Cristina AF Roman, PhD
Clinical neuropsychologist
Neuropsychology
Amy Marie Jaehning, NP-C
Nurse practitioner
Andrew Voyiadjis, MD
Specialized Programs
Multiple Sclerosis Fellowship Program
Multidisciplinary MS care
NMO clinic
MS and Neuroimmunology division
Partnerships & Referral Network
- Roski Eye Institute (Neuroimmunology and Neuro-Ophthalmology collaboration)
- Keck Medicine of USC Pasadena clinic (neurology/MS among multidisciplinary autoimmune services)
Services & Treatments
What They Treat
Multiple sclerosisNeuromyelitis optica spectrum disorderMOG antibody-associated diseaseMOGADNMOAutoimmune encephalitisAutoimmune myelitisParaneoplastic neurologic syndromesNeurosarcoidosisOptic nerve disordersVisual pathway disorders
How They Treat It
Multiple sclerosis careNeuroimmunology careRehabilitationMedical servicesNursing servicesSupport servicesOccupational therapyPhysical therapySocial workNeuro-ophthalmology consultationNeuropsychologyNeuroradiologyNeurosurgery consultationPsychiatryRheumatologySpecialty pharmacyUrologyNeurology consultationTelehealth appointmentsLatest FDA-approved treatmentsClinical trial participationOptical Coherence Tomography (OCT)Visual field testing
Diagnostics
Optical Coherence Tomography (OCT)Visual field testingLatest diagnostic techniquesAdvanced imaging
Research & Clinical Trials
This center is currently involved in 6 clinical trials
A Study to Investigate Long-term Safety and Tolerability of Tolebrutinib in Participants With Multiple Sclerosis.
Sanofi
ACTIVE NOT RECRUITINGPHASE3
TolebrutinibPlaceboTeriflunomide
Central Vein Sign: a Diagnostic Biomarker in Multiple Sclerosis
The Cleveland Clinic
ACTIVE NOT RECRUITING
MRI
Effect of a Fasting Mimicking Diet on Patients With Multiple Sclerosis (FMDMS)
University of Southern California
RECRUITINGNA
Med Diet. Investigators would like to see what differences a Mediterranean Diet makes to the status of patients with Multiple Sclerosis.
Efficacy and Safety Study of Frexalimab (SAR441344) in Adults With Nonrelapsing Secondary Progressive Multiple Sclerosis
Sanofi
RECRUITINGPHASE3
FrexalimabPlaceboMRI contrast-enhancing agents
Phase 2 Basket Trial of Nab-sirolimus in Patients With Malignant Solid Tumors With Pathogenic Alterations in TSC1/TSC2 Genes (PRECISION 1)
Aadi Bioscience, Inc.
ACTIVE NOT RECRUITINGPHASE2
nab-sirolimus
Reduced Oligodendrocyte-specific Cytotoxicity and Ofatumumab Treatment
University of Southern California
ACTIVE NOT RECRUITING
Ofatumumab
Insurance & Access
Contact
Healthcare Consultation Center II, 1520 San Pablo Street Suite 3000, Los Angeles, CA 90033
Insurance & Support
Health Net Covered CaliforniaAnthem Blue Cross Covered CaliforniaTriWest Healthcare Alliance (UHC)ChoiceCare NetworkAnthem Blue Cross Prudent BuyerBlue Shield Covered CaliforniaBlue Shield of CaliforniaHealth Plans of NevadaKern Health SystemsCoventry Health CareFirst HealthPrivate Health Care SystemsGreat-West Healthcare of California, Inc.Brand New DayUnited HealthcareUSC Network
Care Coordinator
Related MS Research
Recent studies relevant to this center's focus areas
FAQs from USC Multiple Sclerosis Comprehensive Care Center
The center treats multiple sclerosis and related conditions such as neuromyelitis optica spectrum disorder, MOG antibody-associated disease, autoimmune encephalitis, autoimmune myelitis, and neurosarcoidosis. It also evaluates optic nerve and visual pathway disorders.
Yes. Telehealth appointments are available for patients who need virtual care.
The team includes neurology, neuro-ophthalmology, neuropsychology, neuroradiology, neurosurgery, nursing, occupational therapy, physical therapy, psychiatry, rheumatology, social work, specialty pharmacy, and urology. This allows many needs to be addressed in one coordinated setting.
Yes. The center has an NMO clinic, and Lilyana Amezcua, MD, serves as medical director of the Neuromyelitis Optica and MOG clinic.
It is affiliated with the University of Southern California, Keck Medicine of USC, and the Keck School of Medicine of USC. The center also offers a multiple sclerosis fellowship program and participates in clinical trial activity.
Compare California MS Centers
| Center | Type | Infusion | Virtual | Experience |
|---|---|---|---|---|
USC Multiple Sclerosis Comprehensive Care Center Los Angeles | Academic MS Center | — | ✓ | 4/5 |
UCSF Multiple Sclerosis Center San Francisco | Academic MS Center | — | — | 3.8/5 |
Cedars-Sinai Multiple Sclerosis Clinic Los Angeles | Academic MS Center | — | — | 3.8/5 |
Stanford MS & Neuroimmunology Clinic Palo Alto | Academic MS Center | — | — | 4/5 |
UC San Diego Health MS Program La Jolla | Academic MS Center | — | — | 3.8/5 |
UCLA Multiple Sclerosis Program Los Angeles | Academic MS Center | — | — | 3.6/5 |
USC Multiple Sclerosis Comprehensive Care Center
Los Angeles • Academic MS Center
Infusion
—
Virtual
✓
Experience
4/5
UCSF Multiple Sclerosis Center
San Francisco • Academic MS Center
Infusion
—
Virtual
—
Experience
3.8/5
Cedars-Sinai Multiple Sclerosis Clinic
Los Angeles • Academic MS Center
Infusion
—
Virtual
—
Experience
3.8/5
Stanford MS & Neuroimmunology Clinic
Palo Alto • Academic MS Center
Infusion
—
Virtual
—
Experience
4/5
UC San Diego Health MS Program
La Jolla • Academic MS Center
Infusion
—
Virtual
—
Experience
3.8/5
UCLA Multiple Sclerosis Program
Los Angeles • Academic MS Center
Infusion
—
Virtual
—
Experience
3.6/5
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Information on this page is compiled from public sources including facility websites, ClinicalTrials.gov, CMS data, and AI analysis. It may not be complete or current. Always verify directly with the facility.