MS Clinical Trials in Illinois

46 active trials · 27 recruiting

46 active multiple sclerosis clinical trials have at least one study site in Illinois, 27 of them currently recruiting participants. Trials are listed from ClinicalTrials.gov and cover disease-modifying therapies, symptom treatments, rehabilitation and imaging studies.

Eligibility, contact details and the exact site address are on each trial's ClinicalTrials.gov record, linked from every trial page. MS Buddy also lists 13 MS treatment centers in Illinois; many trial sites are run from those centers, and your neurologist is the best first person to ask about joining a study.

Active MS trials with sites in Illinois

RecruitingPhase 3

Study to Evaluate Safety, Efficacy and Pharmacokinetics (PK) of a Modified Regimen of Ublituximab

Sponsor: TG Therapeutics, Inc.

Ublituximab · Placebo

25 states800 participantsDetails ›

RecruitingPhase 3

Efficacy and Safety of Remibrutinib After Switching From Ocrelizumab in Participants Living With Relapsing Multiple Sclerosis.

Sponsor: Novartis Pharmaceuticals

Remibrutinib oral treatment · Ocrelizumab

18 states360 participantsDetails ›

RecruitingPhase 1

Nivolumab in Treating Patients With Autoimmune Disorders and Advanced, Metastatic, or Unresectable Cancer

Sponsor: National Cancer Institute (NCI)

Biospecimen Collection · Nivolumab

19 states300 participantsDetails ›

RecruitingNA

Intermittent Hypoxia in Persons With Multiple Sclerosis

Sponsor: Shirley Ryan AbilityLab

Acute Intermittent Hypoxia · Sham-Acute Intermittent Hypoxia

1 state21 participantsDetails ›

RecruitingPhase 4

Ocrelizumab Discontinuation in Relapsing Multiple Sclerosis

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Ocrelizumab · Placebo for Ocrelizumab

9 states123 participantsDetails ›

RecruitingPhase 4

Ublituximab (Briumvi) for Early Forms of Relapsing Multiple Sclerosis

Sponsor: Northwestern University

Ublituximab

1 state40 participantsDetails ›

Recruiting

People With Multiple Sclerosis Treated With Ocrelizumab and GLP-1 Agonists

Sponsor: Northwestern University

GLP-1 · Ocrelizumab (US)

1 state100 participantsDetails ›

RecruitingPhase 3

Efficacy and Safety Studies of Frexalimab (SAR441344) in Adults With Relapsing Forms of Multiple Sclerosis

Sponsor: Sanofi

Frexalimab · Teriflunomide

35 states1600 participantsDetails ›

Recruiting

A Study Evaluating the Real World Experience of Participants Treated With BRIUMVI® (Ublituximab-xiiy) for Relapsing Multiple Sclerosis (RMS)

Sponsor: TG Therapeutics, Inc.

No Intervention

29 states500 participantsDetails ›

RecruitingPhase 3

Efficacy and Safety Study of Frexalimab (SAR441344) in Adults With Nonrelapsing Secondary Progressive Multiple Sclerosis

Sponsor: Sanofi

Frexalimab · Placebo

38 states900 participantsDetails ›

RecruitingNA

Effects of Acute Intermittent Hypoxia on Neuroplasticity in MS

Sponsor: Shirley Ryan AbilityLab

Acute Intermittent Hypoxia · Sham Acute Intermittent Hypoxia

1 state22 participantsDetails ›

RecruitingPhase 3

Study to Evaluate the Effectiveness and Safety of Ozanimod Compared to Fingolimod in Children and Adolescents With Relapsing Remitting Multiple Sclerosis

Sponsor: Celgene

Ozanimod · Fingolimod

9 states194 participantsDetails ›

RecruitingNA

Home Based Functional Balance Intervention for Multiple Sclerosis

Sponsor: University of Illinois at Chicago

Multicomponent balance intervention c… · Stretching

1 state75 participantsDetails ›

RecruitingNA

Internet-Delivered Lifestyle Physical Activity Intervention for Cognitive Processing Speed in Multiple Sclerosis

Sponsor: University of Illinois at Chicago

Behavioral Intervention for Physical … · Wellness for MS (WellMS)

1 state280 participantsDetails ›

RecruitingPhase 3

Best Available Therapy Versus Autologous Hematopoietic Stem Cell Transplant for Multiple Sclerosis (BEAT-MS)

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Autologous Hematopoietic Stem Cell Tr… · Best Available Therapy (BAT)

15 states156 participantsDetails ›

Recruiting

A Biospecimen Collection Study to Identify the Targets of Disease-Reactive T Cells in Patients With Autoimmune Disease

Sponsor: TScan Therapeutics, Inc.

Companion blood samples with procedure

9 states300 participantsDetails ›

RecruitingNA

Examining the Effects of a Remotely-delivered, Racially-tailored Exercise Training Program for Immediate and Sustained Improvements in Walking Dysfunction, Symptoms, and Health-related Quality of Life (HRQOL) Among African-Americans With Multiple Sclerosis (MS) Residing in Rural Environments.

Sponsor: University of Illinois at Chicago

Guidelines for Exercise in Multiple S… · FLEX Stretching and Toning Program

1 state100 participantsDetails ›

RecruitingNA

Evaluation of the Safety and Efficacy of a Full-Body Electrostimulation Garment for Individuals With Neurological and Neuromuscular Conditions That Cause Spasticity, Hyperreflexia, and Pain

Sponsor: Shirley Ryan AbilityLab

Active full-body stimulation · Sham full-body stimulation

1 state15 participantsDetails ›

RecruitingNA

An Individualized-health eLibrary App for People With Multiple Sclerosis

Sponsor: University of Illinois at Urbana-Champaign

SavvyHealth

1 state60 participantsDetails ›

RecruitingNA

Exercise Training for Managing Major Depressive Disorder in Multiple Sclerosis

Sponsor: University of Illinois at Chicago

POWER-MS · FLEX-MS

1 state146 participantsDetails ›

RecruitingNA

Effects of High-intensity Gait Training on Fatigue, Gait, and Neuroplasticity in People With Multiple Sclerosis

Sponsor: University of Illinois at Chicago

treadmill training

1 state20 participantsDetails ›

RecruitingNA

Remote Therapeutic Monitoring Exercise Tracking

Sponsor: Shirley Ryan AbilityLab

Activity Monitoring

1 state200 participantsDetails ›

RecruitingNA

Nomad P-KAFO Study

Sponsor: Shirley Ryan AbilityLab

Indego Nomad® Powered Knee-Ankle-Foot…

1 state36 participantsDetails ›

RecruitingNA

Functional Balance Intervention in Multiple Sclerosis

Sponsor: University of Illinois at Chicago

Functional Balance Intervention · Stretching

1 state120 participantsDetails ›

RecruitingNA

Exercise Rehabilitation Program in MS Who Use Wheelchairs as a Primary Mobility Device

Sponsor: University of Illinois at Chicago

Exercise rehabilitation program

1 state24 participantsDetails ›

Recruiting

Development of Camera Based Gait Quality Measure for Persons With Multiple Sclerosis

Sponsor: Shirley Ryan AbilityLab

Camera Based Kinematic Analysis

1 state40 participantsDetails ›

RecruitingNA

Remote Evaluation of MIND Diet

Sponsor: University of Illinois at Urbana-Champaign

MIND Diet · Control Diet

1 state40 participantsDetails ›

By invitation onlyPhase 4

Quality Improvement and Practice Based Research in Neurology Using the EMR

Sponsor: Endeavor Health

Listed for each disorder below, up to…

1 state3300 participantsDetails ›

Closed to new patientsPhase 2

A Study of LY3541860 in Adult Participants With Relapsing Multiple Sclerosis

Sponsor: Eli Lilly and Company

LY3541860 · Placebo

5 states63 participantsDetails ›

Closed to new patientsPhase 4

Concentration of Ofatumumab in the Breast Milk of Lactating Women With Relapsing Forms of Multiple Sclerosis

Sponsor: Novartis Pharmaceuticals

Ofatunumab

4 states24 participantsDetails ›

Closed to new patients

Sponsor: University of Illinois at Chicago

Aerobic and Resistance Exercise Progr… · Flexibility and Stretching Program (F…

1 state51 participantsDetails ›

Closed to new patientsPhase 2

Study to Evaluate Efficacy, Safety, and Tolerability of IMU-838 in Patients With Progressive Multiple Sclerosis

Sponsor: Immunic AG

IMU-838 · Placebo matching IMU-838

6 states450 participantsDetails ›

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Active MS trials with sites in Illinois

MS trials in other states