Skip to main content

Childhood-Onset MS Research

Updated

Between 2 and 5 in every 100 people with MS first have symptoms before the age of 18. Almost all children with MS, around 98 in every 100, have the relapsing-remitting type. Children usually make a complete recovery after their first attack, but often have more relapses than adults. Below is the latest research on MS in children and teenagers, explained in plain language.

Latest studies

Nov 1, 2026

Childhood MS blood patterns linked to Epstein-Barr virus

Observational study · 175 people with childhood-onset MS and healthy volunteers in Italy

Researchers compared blood from people with childhood-onset MS and healthy volunteers. They found DNA patterns linked to immune activity and Epstein-Barr virus.

Sep 23, 2026

Brain scans found MS groups with different disability

Observational study · 1,953 people with and without MS in two study groups

Brain scans identified four MS groups. Disability and worsening without a relapse differed between groups, but thinking test results did not differ across them.

Nov 6, 2025

Children with MS had fewer relapses on pills or infusions

Observational study · 212 people · children with MS or a first MS-like attack

In a study of 212 children with MS or a first MS-like attack, those switching from shots to pills or infusions had fewer relapses than those switching shots.

Jan 18, 2025

Brain scans show early differences in children with MS

Observational study · 374 children and people with childhood-onset MS, and people without MS

Brain scans of children with MS showed early changes near the brain’s fluid spaces. These changes were linked to brain damage, but not to disability in children.

Dec 21, 2024

When to lower or stop MS treatment remains uncertain

Review · people with MS considering lower doses or stopping treatment

A workshop review examined when people with MS might lower or stop treatment. It discusses aging, pregnancy, childhood-onset MS, and gaps in the evidence.

Dec 1, 2024

Slow-growing brain spots distinguish childhood MS

Observational study · 33 people · children with MS and children with an MS look-alike condition

Repeat scans of 33 children found slowly growing spots in 16 with childhood MS, but just one spot in a group with a condition often mistaken for MS.

Sep 16, 2024

Review guides MS diagnosis in children and older adults

Review · children and older adults with suspected MS

An expert review offers guidance on telling MS from other conditions in children under 18 and adults over 50. It identifies warning signs of a different diagnosis.

MS research roundups by month · All MS research news

The app

Check out the MS Buddy app

Track symptoms, monitor wellness, and stay on top of your MS care. It’s free, with no ads. Built by people living with MS.

Download on the App StoreGet it on Google Play