19 Active TrialsInfusion CenterVirtual CareLarge Center
15 MS centers statewide · Ranked #1 in Ohio for clinical trials
What kind of place is this?
Comprehensive Care TeamResearch FocusedVirtual Care Available
You’re looking at a large academic MS center where care is organized around both treatment and research. You’ll likely appreciate the broad team, advanced testing, infusion services, and the option for virtual visits. Because this is a busy specialty center, your care may involve multiple teams working together across a large program.
Facility Profile
Synthesized from this facility's public website and data sources. Not a recommendation or ranking — just a summary to help you orient.
Direct Doctor Access2/5
Support Services5/5
Clinical Trials & Research4/5
Insurance & Navigation Help3/5
Scheduling & Virtual Care5/5
About Mellen Center for MS Treatment & Research
This center combines high-volume MS care with active research within a large academic medical setting. It is also known for the first 7 Tesla MRI in Northeast Ohio, which adds advanced imaging capability to the care experience.
Mellen Center for MS Treatment & Research cares for people with multiple sclerosis and related neurologic conditions, including pediatric MS, optic neuritis, transverse myelitis, and neuromyelitis optica. You can receive care from a multidisciplinary team that includes neurologists, nurses, therapists, psychologists, social workers, and research specialists. Services include imaging and diagnostic testing, rehabilitation, infusion therapy, health psychology, and alternative and complementary medicine appointments. The center also offers virtual visits, MyChart support, and a strong connection to MS research.
Good to know
- Virtual visits are available for both new and existing patients.
- Onsite infusion services are available.
- MyChart lets you message your care team and manage appointments.
- Patients can request image uploads and image copies.
- A care coordinator is available to help support your visit planning.
Mellen Center for Multiple Sclerosis brings together a large team focused on MS care and research within a major academic health system. Patients can access in-person and virtual visits, infusion services, rehabilitation, and a patient portal for messaging and appointment management. The center also stands out for offering the first 7 Tesla MRI in Northeast Ohio.
Specialized Programs
Pediatric multiple sclerosis
Rehabilitation
Health psychology
Alternative and complementary medicine appointments
Driver rehabilitation program
Multiple sclerosis research programs
Brain study
Services & Treatments
What They Treat
Multiple sclerosisRelapsing-remitting multiple sclerosisPrimary progressive multiple sclerosisSecondary progressive multiple sclerosisPediatric multiple sclerosisNeuromyelitis opticaAnti-MOG-associated diseaseAutoimmune encephalitisAutoimmune neurological disordersOptic neuritisSpasticityTransverse myelitisAcute disseminated encephalomyelitis
How They Treat It
Multiple sclerosis careClinical trialsResearch programsVirtual visitsIn-person appointmentsRehabilitation servicesInfusion servicesMyChart patient messaging and appointment managementImage request and image uploadReferral services for medical professionalsAlternative and complementary therapiesDisease modifying agentsDriver rehabilitation programHealth psychologyInfusion therapyIV steroidsNeurorehabilitation servicesOccupational therapyBotox for spasticityStem cell therapiesRobotic exoskeleton rehabilitationVirtual reality rehabilitation
Diagnostics
Evoked potentialsLumbar punctureMagnetic resonance imaging (MRI)Neuropsychological evaluationsOptical coherence tomographyMultiple Sclerosis Performance Test7 Tesla MRI
Research & Clinical Trials
This center is currently involved in 19 clinical trials — ranked #1 in Ohio for active trials
A Study of Ocrelizumab in Children and Adolescents With Relapsing-Remitting Multiple Sclerosis
Hoffmann-La Roche
ACTIVE NOT RECRUITINGPHASE2
Ocrelizumab
A Study to Evaluate Ocrelizumab Treatment in Participants With Progressive Multiple Sclerosis
Hoffmann-La Roche
ACTIVE NOT RECRUITINGPHASE3
Ocrelizumab
A Study to Evaluate Safety and Efficacy of Ocrelizumab in Comparison With Fingolimod in Children and Adolescents With Relapsing-Remitting Multiple Sclerosis (RRMS)
Hoffmann-La Roche
ACTIVE NOT RECRUITINGPHASE3
OcrelizumabOcrelizumab PlaceboFingolimodFingolimod Placebo
A Study to Evaluate the Efficacy, Safety and Pharmacokinetics (PK) of a Higher Dose of Ocrelizumab in Adults With Primary Progressive Multiple Sclerosis (PPMS)
Hoffmann-La Roche
ACTIVE NOT RECRUITINGPHASE3
OcrelizumabOcrelizumabAntihistamineMethylprednisolone
A Study to Evaluate the Safety, Tolerability, Efficacy, and Drug Levels of CC-97540 in Participants With Relapsing Forms of Multiple Sclerosis, Progressive Forms of Multiple Sclerosis or Refractory Myasthenia Gravis (MG) (Breakfree-2)
Juno Therapeutics, Inc., a Bristol-Myers Squibb Company
RECRUITINGPHASE1
CC-97540FludarabineCyclophosphamide
A Study to Investigate Long-term Safety and Tolerability of Tolebrutinib in Participants With Multiple Sclerosis.
Sanofi
ACTIVE NOT RECRUITINGPHASE3
TolebrutinibPlaceboTeriflunomide
ABA-101 in Participants With Progressive Multiple Sclerosis
Abata Therapeutics
ACTIVE NOT RECRUITINGPHASE1
ABA-101
AMT-260 Gene Therapy Study in Adults With Unilateral Refractory Mesial Temporal Lobe Epilepsy
UniQure Biopharma B.V.
RECRUITINGPHASE1, PHASE2
AAV9-hSyn1-miGRIK2
Best Available Therapy Versus Autologous Hematopoietic Stem Cell Transplant for Multiple Sclerosis (BEAT-MS)
National Institute of Allergy and Infectious Diseases (NIAID)
RECRUITINGPHASE3
Autologous Hematopoietic Stem Cell TransplantationBest Available Therapy (BAT)
Care in Multiple Sclerosis (MS)
NYU Langone Health
RECRUITING
Central Vein Sign in Multiple Sclerosis Extension Study
The Cleveland Clinic
RECRUITINGNA
MRI Contrast
Central Vein Sign: a Diagnostic Biomarker in Multiple Sclerosis
The Cleveland Clinic
ACTIVE NOT RECRUITING
MRI
Determining the Effectiveness of earLy Intensive Versus Escalation Approaches for RRMS
The Cleveland Clinic
ACTIVE NOT RECRUITINGPHASE4
Early Highly Effective Therapies GroupEscalation Therapies Group
Long-term Safety, Tolerability and Effectiveness Study of Ofatumumab in Patients With Relapsing MS
Novartis Pharmaceuticals
ACTIVE NOT RECRUITINGPHASE3
OfatumumabTetanus toxoid (TT) containing vaccine (Td, Tdap)13-valent pneumococcal conjugate vaccine (13-PCV)23-valent pneumococcal polysaccharide vaccine (23-PPV)Seasonal Quadrivalent influenza vaccineKeyhole limpet hemocyanin (KLH) neo-antigen
Phase 2 Basket Trial of Nab-sirolimus in Patients With Malignant Solid Tumors With Pathogenic Alterations in TSC1/TSC2 Genes (PRECISION 1)
Aadi Bioscience, Inc.
ACTIVE NOT RECRUITINGPHASE2
nab-sirolimus
Prospective Evaluation of Sequencing From antiCD-20 Therapies to Ozanimod
University of Colorado, Denver
RECRUITINGPHASE4
Ozanimod
RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses
Reunion Neuroscience Inc
RECRUITINGPHASE2
RE104 for Injection
TSC Biosample Repository and Natural History Database
National Tuberous Sclerosis Association
RECRUITING
PhlebotomyBuccal (cheek) swabGenetic TestingTissue donation after routine clinical procedure
VIRtual Versus UsuAL In-office Care for Multiple Sclerosis (VIRTUAL-MS)
The Cleveland Clinic
ACTIVE NOT RECRUITINGNA
Multiple Sclerosis Clinical Care Delivery via telehealthMultiple Sclerosis Clinical Care Delivery via standard in clinic visits
Insurance & Access
Contact
Cleveland Clinic Foundation, 9500 Euclid Avenue, U-10, Cleveland, OH 44195-5244
Insurance & Support
Care Coordinator
Patient Portal
Related MS Research
Recent studies relevant to this center's focus areas
FAQs from Mellen Center for MS Treatment & Research
The center treats multiple sclerosis, including relapsing-remitting, primary progressive, and secondary progressive forms. It also cares for pediatric MS, neuromyelitis optica, anti-MOG-associated disease, optic neuritis, transverse myelitis, and acute disseminated encephalomyelitis.
Yes. The center has active clinical trials and research programs, along with a dedicated MS research focus.
Yes, the center has an onsite infusion model and offers infusion services. IV steroids are also among the treatments mentioned.
The center offers MRI, including 7 Tesla MRI, along with evoked potentials, lumbar puncture, neuropsychological evaluations, optical coherence tomography, and the Multiple Sclerosis Performance Test.
You can use MyChart for messaging and appointment management. The center also offers virtual visits and provides image request and upload support.
Compare Ohio MS Centers
| Center | Type | Infusion | Virtual | Experience |
|---|---|---|---|---|
Mellen Center for MS Treatment & Research Cleveland | Academic MS Center | ✓ | ✓ | 3.8/5 |
| Academic MS Center | — | — | 4/5 | |
| Academic MS Center | — | — | 3.6/5 | |
| Dedicated MS Practice | — | — | 3.6/5 | |
Dayton Center for Neurological Disorders Centerville | Regional Neurology Group | — | — | 3.4/5 |
Nationwide Children's Hospital Columbus | Academic MS Center | — | — | 2.8/5 |
Mellen Center for MS Treatment & Research
Cleveland • Academic MS Center
Infusion
✓
Virtual
✓
Experience
3.8/5
Cincinnati Children's MS and Neuroimmunology Center
Cincinnati • Academic MS Center
Infusion
—
Virtual
—
Experience
4/5
The Waddell Center for Multiple Sclerosis
Cincinnati • Academic MS Center
Infusion
—
Virtual
—
Experience
3.6/5
The Boster Center for Multiple Sclerosis a Singlepoint Healthcare Company
Columbus • Dedicated MS Practice
Infusion
—
Virtual
—
Experience
3.6/5
Dayton Center for Neurological Disorders
Centerville • Regional Neurology Group
Infusion
—
Virtual
—
Experience
3.4/5
Nationwide Children's Hospital
Columbus • Academic MS Center
Infusion
—
Virtual
—
Experience
2.8/5
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Information on this page is compiled from public sources including facility websites, ClinicalTrials.gov, CMS data, and AI analysis. It may not be complete or current. Always verify directly with the facility.