Thomas Jefferson University Comprehensive MS Center

Philadelphia, Pennsylvania

Academic MS Center
9 Active TrialsInfusion CenterVirtual CareLarge Center
15 MS centers statewide · Ranked #1 in Pennsylvania for clinical trials · #2 in Pennsylvania for provider count
What kind of place is this?
Comprehensive Care TeamResearch FocusedPart of Major Health System

You are coming to a large academic MS center where your care can be coordinated across neurology, rehab, and other specialties. You may appreciate the infusion therapy options, support groups, wellness programming, and virtual care access.

Facility Profile
Synthesized from this facility's public website and data sources. Not a recommendation or ranking — just a summary to help you orient.
Direct Doctor Access2/5
Support Services5/5
Clinical Trials & Research3/5
Insurance & Navigation Help3/5
Scheduling & Virtual Care4/5

About Thomas Jefferson University Comprehensive MS Center

This center combines MS care with a wide range of related services, including rehabilitation, infusion therapy, spasticity care, and advanced treatments such as baclofen pump management and deep brain stimulation. It is also connected to Jefferson Health and Jefferson Moss-Magee Rehabilitation, bringing multiple specialties together in one coordinated setting.

Thomas Jefferson University Comprehensive MS Center cares for people living with multiple sclerosis, including relapsing-remitting, secondary progressive, and primary progressive forms, as well as related conditions like spasticity and transverse myelitis. You can access diagnosis and treatment, infusion therapy, oral and injectable medications, first-dose monitoring, and support for self-administered medicines. The center also offers rehabilitation, baclofen pump management, Botox injections for muscle spasms, and deep brain stimulation when appropriate. As part of Jefferson Health and its neuroscience and rehabilitation partnerships, it brings together multiple specialties in one coordinated setting.

Thomas Jefferson University Comprehensive MS Center in Philadelphia is an academic MS center within Jefferson Health. You get care from a multidisciplinary team that can include neurologists, rehabilitation specialists, therapists, and mental health professionals. It also offers infusion therapy, rehabilitation, support groups, and wellness programming to support you beyond diagnosis and treatment.

Featured Care Team Members

Silva Markovic-Plese, MD
Active MS Prescriber

Specialized Programs

MS Rehabilitation
MS Support Group at Elkins Park
MS Healthy Living
Lifetime follow-up care system
Specialized rehabilitation services

Partnerships & Referral Network

  • Jefferson Moss-Magee Rehabilitation (rehabilitation services and follow-up care)
  • Vickie & Jack Farber Institute for Neuroscience (MS care and research)

Services & Treatments

What They Treat
Multiple sclerosisRelapsing-remitting multiple sclerosisSecondary progressive multiple sclerosisPrimary progressive multiple sclerosisSpasticityTransverse myelitis
How They Treat It
MS diagnosis and treatmentMultidisciplinary MS careMS rehabilitationSpasticity careTransverse myelitis careInfusion therapyOral and injectable treatmentsFirst-dose monitoringSupport for self-administered medicationsBaclofen pump managementBotox injections for muscle spasmsDeep brain stimulationPatient support groupsWellness programmingBaclofen pump implantation and maintenanceBotulinum toxin injectionsDeep brain stimulationInfusion therapyOral therapiesInjectable therapiesFirst-dose monitoringSelf-administered medication supportPhysical therapyRehabilitation therapyMassage therapyIntrathecal baclofen therapy
Diagnostics
MRIAdvanced MRI technologyGEM MRI technology3 Tesla MRI

Research & Clinical Trials

This center is currently involved in 9 clinical trials — ranked #1 in Pennsylvania for active trials

A Study of Nasal Foralumab in Non-Active Secondary Progressive Multiple Sclerosis Patients
Tiziana Life Sciences LTD
RECRUITINGPHASE2
ForalumabPlacebo
Efficacy and Safety Studies of Frexalimab (SAR441344) in Adults With Relapsing Forms of Multiple Sclerosis
Sanofi
RECRUITINGPHASE3
FrexalimabTeriflunomidePlacebo infusionPlacebo tabletMRI contrast-enhancing agentsCholestyramineActivated charcoal
Efficacy and Safety Study of Frexalimab (SAR441344) in Adults With Nonrelapsing Secondary Progressive Multiple Sclerosis
Sanofi
RECRUITINGPHASE3
FrexalimabPlaceboMRI contrast-enhancing agents
Long-term Safety, Tolerability and Effectiveness Study of Ofatumumab in Patients With Relapsing MS
Novartis Pharmaceuticals
ACTIVE NOT RECRUITINGPHASE3
OfatumumabTetanus toxoid (TT) containing vaccine (Td, Tdap)13-valent pneumococcal conjugate vaccine (13-PCV)23-valent pneumococcal polysaccharide vaccine (23-PPV)Seasonal Quadrivalent influenza vaccineKeyhole limpet hemocyanin (KLH) neo-antigen
Nivolumab in Treating Patients With Autoimmune Disorders and Advanced, Metastatic, or Unresectable Cancer
National Cancer Institute (NCI)
RECRUITINGPHASE1
Biospecimen CollectionNivolumab
Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of a New Maintenance Dosing Regimen of Ofatumumab
Novartis Pharmaceuticals
ACTIVE NOT RECRUITINGPHASE3
Ofatumumab approved doseOfatumumab new dose
Phase 2 Basket Trial of Nab-sirolimus in Patients With Malignant Solid Tumors With Pathogenic Alterations in TSC1/TSC2 Genes (PRECISION 1)
Aadi Bioscience, Inc.
ACTIVE NOT RECRUITINGPHASE2
nab-sirolimus
Physiological Effects of N-Acetyl Cysteine in Patients With Multiple Sclerosis
Thomas Jefferson University
ENROLLING BY INVITATIONNA
N-acetyl Cysteine
Study of COYA 302 for the Treatment of ALS
Coya Therapeutics
RECRUITINGPHASE2
COYA 302Placebo

Insurance & Access

Contact
900 Walnut Street Suite 200, Philadelphia, PA 19107-5083
Insurance & Support
Care Coordinator
Patient Portal
Support Groups

FAQs from Thomas Jefferson University Comprehensive MS Center

You can receive diagnosis and treatment for multiple sclerosis along with multidisciplinary care. The center also supports related needs such as spasticity care, rehabilitation, infusion therapy, and medication support.

Yes. Infusion therapy is available, and the center also supports oral, injectable, and self-administered medications. First-dose monitoring is available when starting certain treatments.

Yes. The center offers MS support groups and wellness programming, including art therapy, horticultural therapy, exercise programs, dance movement programs, educational activities, and circuit-training.

Yes. Rehabilitation is part of the care plan, with support from physical therapists, occupational therapists, speech therapists, and rehabilitation medicine specialists. The center also offers specialized MS rehabilitation services.

You can schedule an appointment through Jefferson Health at 215-955-6000 or use the online scheduling option. Telehealth visits are also available.

Check out the MS Buddy App

Track symptoms, monitor wellness, and stay on top of your MS care. It's free, no ads. How? It's made and supported by MS patients who get their ideas from other MS patients.

Download on the App StoreGet it on Google Play
Call Website Book