UCI Health Multiple Sclerosis Program

Orange, California

Dedicated MS Practice
7 Active TrialsMedium Practice
30 MS centers statewide · Ranked #5 in California for clinical trials
What kind of place is this?
Comprehensive Care TeamResearch FocusedPart of Major Health System

You’re in a dedicated MS center where your care is shaped by a team of specialists and support staff working together. You’ll likely appreciate the range of services, from advanced testing and rehabilitation to pharmacy and social work support. You should know this is a single-location program, and new patient appointments are scheduled by phone.

Facility Profile
Synthesized from this facility's public website and data sources. Not a recommendation or ranking — just a summary to help you orient.
Direct Doctor Access4/5
Support Services5/5
Clinical Trials & Research4/5
Insurance & Navigation Help3/5
Scheduling & Virtual Care2/5

About UCI Health Multiple Sclerosis Program

This center pairs MS specialists with a broad support team, including an MS nurse navigator and MS nurse practitioner, so your care stays coordinated.

UCI Health Multiple Sclerosis Program serves people living with multiple sclerosis through coordinated neurologic care, testing, and rehabilitation support. You can access services such as MRI collaboration, biomarker testing, spinal fluid tests, evoked potentials, optical coherence spectroscopy, and rehabilitation therapies. The team also includes pharmacists, nurses, physical therapists, occupational therapists, and social workers, which helps support both treatment and day-to-day care. The program offers a patient portal for ongoing communication and follow-up.

UCI Health Multiple Sclerosis Program is a dedicated MS center in Orange that brings together specialists, imaging, pharmacy, therapy, and social work support in one coordinated setting. You are cared for by a team that includes three named MS specialists, an MS nurse navigator, and an MS nurse practitioner. It is part of UCI Health, giving you access to a larger academic health system.

Featured Care Team Members

Michael Demetriou, MD, PhD
Multiple sclerosis specialist
Multiple sclerosis
Michael Y. Sy, MD, PhD
Multiple sclerosis specialist
Multiple sclerosis
Gaby T. Thai, MD
Multiple sclerosis specialist
Multiple sclerosis

Specialized Programs

Comprehensive care clinic
Research program
Clinical trials access
MS specialist program

Services & Treatments

What They Treat
Multiple sclerosis
How They Treat It
Multiple sclerosis careNeurology careMultidisciplinary MS careMRI collaborationPharmacy servicesOccupational therapyPhysical therapySocial work supportNursing supportMS nurse navigator supportMS nurse practitioner careDisease modifying therapyCognitive therapyLifestyle changesNeurologic rehabilitationOccupational therapyPhysical therapy
Diagnostics
Magnetic resonance imaging (MRI)Biomarker testCerebrospinal fluid testsEvoked potentials (EP)Magnetic resonance spectroscopy (MRS)Nuclear medicine testingOptical coherence tomography (OCT)

Research & Clinical Trials

This center is currently involved in 7 clinical trials — ranked #5 in California for active trials

A Study to Evaluate the Efficacy and Safety of Fenebrutinib Compared With Teriflunomide in Relapsing Multiple Sclerosis (RMS)
Hoffmann-La Roche
ACTIVE NOT RECRUITINGPHASE3
FenebrutinibTeriflunomidePlacebo
A Study to Evaluate the Efficacy, Safety and Pharmacokinetics (PK) of a Higher Dose of Ocrelizumab in Adults With Primary Progressive Multiple Sclerosis (PPMS)
Hoffmann-La Roche
ACTIVE NOT RECRUITINGPHASE3
OcrelizumabOcrelizumabAntihistamineMethylprednisolone
A Study to Evaluate the Safety, Tolerability, Efficacy, and Drug Levels of CC-97540 in Participants With Relapsing Forms of Multiple Sclerosis, Progressive Forms of Multiple Sclerosis or Refractory Myasthenia Gravis (MG) (Breakfree-2)
Juno Therapeutics, Inc., a Bristol-Myers Squibb Company
RECRUITINGPHASE1
CC-97540FludarabineCyclophosphamide
Efficacy and Safety Studies of Frexalimab (SAR441344) in Adults With Relapsing Forms of Multiple Sclerosis
Sanofi
RECRUITINGPHASE3
FrexalimabTeriflunomidePlacebo infusionPlacebo tabletMRI contrast-enhancing agentsCholestyramineActivated charcoal
Efficacy and Safety Study of Frexalimab (SAR441344) in Adults With Nonrelapsing Secondary Progressive Multiple Sclerosis
Sanofi
RECRUITINGPHASE3
FrexalimabPlaceboMRI contrast-enhancing agents
Evaluation of MN-166 (Ibudilast) for 12 Months Followed by an Open-label Extension for 6 Months in Patients With ALS
MediciNova
ACTIVE NOT RECRUITINGPHASE2, PHASE3
MN-166placebo
Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of a New Maintenance Dosing Regimen of Ofatumumab
Novartis Pharmaceuticals
ACTIVE NOT RECRUITINGPHASE3
Ofatumumab approved doseOfatumumab new dose

Insurance & Access

Contact
Dept of Neurology, 200 S Manchester Ave Ste 200, Orange, CA 92686
Insurance & Support
Care Coordinator
Patient Portal

FAQs from UCI Health Multiple Sclerosis Program

You can receive multiple sclerosis care, neurology care, and multidisciplinary MS support in one place. The team also offers pharmacy services, nursing support, social work, occupational therapy, and physical therapy.

Yes. The program works with MRI and also offers biomarker testing, cerebrospinal fluid tests, evoked potentials, magnetic resonance spectroscopy, nuclear medicine testing, and optical coherence tomography.

The named MS specialists are Michael Demetriou, MD, PhD; Michael Y. Sy, MD, PhD; and Gaby T. Thai, MD. The broader care team also includes neurologists, radiologists, pharmacists, therapists, nurses, and social workers.

The program uses a multidisciplinary team and includes an MS nurse navigator to help coordinate care.

New patient appointments are scheduled by phone at 714-456-7720. The program also offers a patient portal for follow-up and communication after you are established.

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